Cancers, Vol. 13, Pages 1647: Current Status and Future Perspectives of Perioperative Therapy for Resectable Biliary Tract Cancer: A Multidisciplinary Review
Cancers, Vol. 13, Pages 1647: Current Status and Future Perspectives of Perioperative Therapy for Resectable Biliary Tract Cancer: A Multidisciplinary Review
Cancers doi: 10.3390/cancers13071647
Authors:
Changhoon Yoo
Sang-Hyun Shin
Joon-Oh Park
Kyu-Pyo Kim
Jae-Ho Jeong
Baek-Yeol Ryoo
Woohyung Lee
Ki-Byung Song
Dae-Wook Hwang
Jin-Hong Park
Jae-Hoon Lee
Biliary tract cancers (BTCs) are a group of aggressive malignancies that arise from the bile duct and gallbladder. BTCs include intrahepatic cholangiocarcinoma (IH-CCA), extrahepatic cholangiocarcinoma (EH-CCA), and gallbladder cancer (GBCA). BTCs are highly heterogeneous cancers in terms of anatomical, clinical, and pathological characteristics. Until recently, the treatment of resectable BTC, including surgery, adjuvant chemotherapy, and radiation therapy, has largely been based on institutional practice guidelines and evidence from small retrospective studies. Recently, several large randomized prospective trials have been published, and there are ongoing randomized trials for resectable BTC. In this article, we review prior and recently updated evidence regarding surgery, adjuvant and neoadjuvant chemotherapy, and adjuvant radiation therapy for patients with resectable BTC.
Source: Cancers - Category: Cancer & Oncology Authors: Changhoon Yoo Sang-Hyun Shin Joon-Oh Park Kyu-Pyo Kim Jae-Ho Jeong Baek-Yeol Ryoo Woohyung Lee Ki-Byung Song Dae-Wook Hwang Jin-Hong Park Jae-Hoon Lee Tags: Review Source Type: research