Serum neurofilament light chain is a biomarker of human spinal cord injury severity and outcome

Conclusions
Serum NfL concentrations in SCI patients show a close correlation with acute severity and neurological outcome. Our data provide evidence that serum NfL is of prognostic value in SCI patients for the first time. Further, blood NfL levels may qualify as drug response markers in SCI.

Source: Journal of Neurology, Neurosurgery and Psychiatry - February 12, 2015 Category: Neurosurgery Authors: Kuhle, J., Gaiottino, J., Leppert, D., Petzold, A., Bestwick, J. P., Malaspina, A., Lu, C.-H., Dobson, R., Disanto, G., Norgren, N., Nissim, A., Kappos, L., Hurlbert, J., Yong, V. W., Giovannoni, G., Casha, S. Tags: Immunology (including allergy), Neurological injury, Spinal cord, Stroke, Trauma CNS / PNS, Trauma, Injury Spinal cord injury Source Type: research