Effects of different exercise modalities on cardiac dysfunction in heart failure with preserved ejection fraction

ConclusionsIn this metabolic rat model of HFpEF at an advanced stage, Ca2+ release was impaired under baseline conditions. HIIT and MICT differentially affected Ca2+ homeostasis with positive effects of MICT on stroke volume, end ‐diastolic volume, and cellular arrhythmogenicity.

Source: ESC Heart Failure - March 26, 2021 Category: Cardiology Authors: David Bode, Natale P.L. Rolim, Tim Guthof, Niklas Hegemann, Paulina Wakula, Uwe Primessnig, Anne Marie Ormbostad Berre, Volker Adams, Ulrik Wisl øff, Burkert M. Pieske, Frank R. Heinzel, Felix Hohendanner, OptimEx Study Group Tags: Original Research Article Source Type: research