Situation of Rabies in Ethiopia: A Five-Year Retrospective Study of Human Rabies in Addis Ababa and the Surrounding Regions
CONCLUSION: Mechanisms must be sought to reduce the cost of PEP and means of obtaining funds so as to initiate timely treatment for rabies exposed individuals of low socioeconomic status. Besides prevention, strategies should focus on public education and strict dog population control.PMID:33679992 | PMC:PMC7910060 | DOI:10.1155/2021/6662073
AbstractRabies is an important zoonotic disease in Iran. Autophagy is a process that maintains homeostasis and can be used as an innate defense mechanism against viruses. Apoptosis is the process of programmed cell death induced by physiological and pathological conditions. The crosstalk of autophagy and apoptosis plays a key role in rabies virus infection. In the current study, NMRI mice intra-cranially received 3-Methyl Adenine (3-MA), rapamycin, street rabies virus (SRABV) and drugs plus SRABV. SRABV andMap1lc3,Beclin-1,Atg5 gene expression were assayed by real-time PCR. Immunohistochemistry was carried out via LC3 prot...
Publication date: Available online 2 October 2020Source: Comparative Immunology, Microbiology and Infectious DiseasesAuthor(s): Namera Thahaby, Afzal Hoque Akand, Shabeer Ahmed Hamdani, Abdul Hai Bhat, Syed Akram Hussain, Islamuddin Shiekh, Sheikh Shubeena
(Virginia Tech) Renowned tick immunobiologist Utpal Pal wants to adapt the rabies vaccination platform to produce antibodies that can protect against Borrelia burgdorferi, the bacteria responsible for Lyme disease. The intention is to apply this work to other tick-borne diseases in the future.
Publication date: Available online 28 September 2020Source: Preventive Veterinary MedicineAuthor(s): Yong-chao Qiao, Feng Wang, Yong-ling He, Qiu Yang, Jun Yang, Ye-sheng Wei
Dog vaccination programs are the most effective way to prevent Rabies Rabies is endemic to over 150 countries, and according to the World Health Organization, 99% of all transmissions to humans are from dogs, potentially bringing into question the animal’s status as the ‘man’s best friend’. In Europe, southern Africa, and parts of North America, most cases are acquired from wild carnivores; mongooses, and vampire bats in Latin America and the Caribbean. In more recent years, humans have acquired rabies from inhalation of aerosols in bat caves, ingestion of dogs and cats for food, ticks...
[The Conversation Africa] Before the emergence of the newest animal-borne disease, COVID-19, the world was in the last mile of eliminating one of the oldest animal-borne diseases - rabies.
Boehringer Ingelheim steps up its efforts to eliminate rabies through sustainable programs Vaccinating dogs most effective to protect human lives Boehringer Ingelheim supports local self-sustaining programs that fight rabies Contributing to continuous rabies awareness and vaccination campaigns key to the company ’s strategy
Abstract Although canine rabies virus variant (CRVV) was successfully eliminated from the United States after approximately 6 decades of vaccination campaigns, licensing requirements, and stray animal control, dogs remain the principal source of human rabies infections worldwide. A rabies vaccination certificate is required for dogs entering the United States from approximately 100 countries with endemic CRVV, including Egypt (1). On February 25, 2019, rabies was diagnosed in a dog imported from Egypt, representing the third canine rabies case imported from Egypt in 4 years (2,3). This dog and 25 others were impor...
This report describes an instance of canine rabies in a rescue dog imported from Egypt.
ConclusionsThe change in rabies PrEP and PEP recommendations in 2018 reduced total costs. Strategies with increased pre-travel vaccination uptake led to fewer RIG administrations and fewer vaccinations after exposure but also to higher total costs. Although larger scale intradermal administration of rabies vaccine can reduce total costs of PrEP and can positively influence vaccination uptake, it remains a costly intervention.