Cardiovascular magnetic resonance stress and rest T1-mapping using regadenoson for detection of ischemic heart disease compared to healthy controls
Adenosine stress T1-mapping on cardiovascular magnetic resonance (CMR) can differentiate between normal, ischemic, infarcted, and remote myocardial tissue classes without the need for contrast agents. Regadenoson, a selective coronary vasodilator, is often used in stress perfusion imaging when adenosine is contra-indicated, and has advantages in ease of administration, safety profile, and clinical workflow. We aimed to characterize the regadenoson stress T1-mapping response in healthy individuals, and to investigate its ability to differentiate between myocardial tissue classes in patients with coronary artery disease (CAD).
Source: International Journal of Cardiology - Category: Cardiology Authors: Matthew K. Burrage, Mayooran Shanmuganathan, Ambra Masi, Evan Hann, Qiang Zhang, Iulia A. Popescu, Rajkumar Soundarajan, Joana Leal Pelado, Kelvin Chow, Stefan Neubauer, Stefan K. Piechnik, Vanessa M. Ferreira Source Type: research