Value of a 21-gene expression assay on core biopsy to predict neoadjuvant chemotherapy response in breast cancer: systematic review and meta-analysis

CONCLUSION: A high recurrence score is associated with higher pCR rates and a low-intermediate recurrence score may indicate chemoresistance. Routine assessment of recurrence score by the 21-gene expression assay on core biopsy might be of value when considering neoadjuvant chemotherapy in patients with ER-positive, HER2-negative breast cancer.PMID:33640948 | DOI:10.1093/bjs/znaa048

Source: The British Journal of Surgery - February 28, 2021 Category: Surgery Authors: M R Boland A Al-Maksoud É J Ryan I Balasubramanian J Geraghty D Evoy D McCartan R S Prichard E W McDermott Source Type: research