Intravenous methadone causes acute toxic and delayed inflammatory encephalopathy with persistent neurocognitive impairments

The mu-opioid agonist methadone is administered orally and used in opioid detoxification and in the treatment of moderate-to-severe pain. Acute oral methadone –use and –abuse have been associated with inflammat...

Source: BMC Neurology - February 22, 2021 Category: Neurology Authors: Jonathan Repple, Svea Haessner, Andreas Johnen, Nils C. Landmeyer, Andreas Schulte-Mecklenbeck, Marc Pawlitzki, Heinz Wiendl and Gerd Meyer zu H örste Tags: Case report Source Type: research