Effect of gingival mesenchymal stem cell-derived exosomes on inflammatory macrophages in a high-lipid microenvironment.

CONCLUSIONS: GMSC-Exos reduce the release level and expression of inflammatory factors, inhibit lipid accumulation, and promote the polarization of pro-inflammatory macrophages into anti-inflammatory phenotype in a high-lipid microenvironment.
PMID: 33582592 [PubMed - as supplied by publisher]

Source: International Immunopharmacology - February 11, 2021 Category: Allergy & Immunology Authors: Zhang Y, Wang Z, Shi B, Li Y, Wang R, Sun J, Hu Y, Yuan C, Xu Q Tags: Int Immunopharmacol Source Type: research