RNF115 promotes lung adenocarcinoma through Wnt/ β-catenin pathway activation by mediating APC ubiquitination

ConclusionThe current study reveals a close association between RNF115 expression and prognostic conditions in LUAD patients and the oncogenic roles of RNF115 in LUAD at the first time. These findings may help establish the foundation for the development of therapeutics strategies and clinical management for lung cancer in future.
Source: Cancer and Metabolism - Category: Cancer & Oncology Source Type: research