Patient iPSC-derived retinal organoids: Observable retinal diseases in-a-dish.

Patient iPSC-derived retinal organoids: Observable retinal diseases in-a-dish. Histol Histopathol. 2021 Jan 22;:18307 Authors: Zhang XH, Jin ZB Abstract Induced pluripotent stem cells (iPSCs), reprogrammed from human somatic cells, hold the capacity to differentiate into most human body cells. iPSCs can be differentiated into retinal organoids, a three-dimensional structured retina containing various retinal cells. Patient-specific retinal organoids provide a powerful disease model to recapitulate the disease to study the pathogenesis of inherited retinal dystrophies, to screen or discover new drugs, and most importantly to supply an unlimited cell source for retinal regeneration. PMID: 33491763 [PubMed - as supplied by publisher]
Source: Histology and Histopathology - Category: Cytology Tags: Histol Histopathol Source Type: research