Risk of development of brain metastases according to the IASLC/ATS/ERS lung adenocarcinoma classification in advanced and metastatic disease

Lung cancer is a health problem of global proportions. Even though lung cancer shows a declining incidence and mortality globally, it remains the leading cause of cancer-related death worldwide. [1,2] Approximately 16 to 22% of all advanced non-small-cell lung cancer (NSCLC) patients had BM at diagnosis, and up to 30-54% will develop them throughout the disease [3]. Lung Adenocarcinoma (LADC) represents more than 50% of current cases and is strongly related to central nervous involvement (24-35.7%) compared to other histologies.

Source: Lung Cancer - January 27, 2021 Category: Cancer & Oncology Authors: Oscar Arrieta, Alejandro Avil és Salas, Andrés F. Cardona, Diego Díaz-García, Luis Lara-Mejía, Ixel Escamilla, Ariana Pereira García, Enrique Caballé Pérez, Luis E. Raez, Christian Rolfo, Rafael Rosell Source Type: research