De novo adult acute myeloid leukemia with two new mutations in juxtatransmembrane domain of the FLT3 gene: a case report

ConclusionsTo the best of our knowledge, a combination of twoFLT3-ITD mutations in JMD together with anNPM1 type A mutation were not previously reported in adult AML. Further studies are necessary to prove or rule out whether the size of theseFLT3-ITDs mutations and potential other double mutations inFLT3-ITD are correlated with the observed adverse outcome.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research