Quantifying the advantages of conducting a prospective meta-analysis (PMA): a case study of early childhood obesity prevention

ConclusionProspective planning led to greater outcome harmonisation and greater power to detect intervention effects, while maintaining acceptable variation in trial designs and populations, which improved external validity. Recommendations for future PMA include more detailed harmonisation of outcome measures and careful pre-specification of analyses to avoid research waste by unnecessary over-collection of data.
Source: Trials - Category: Research Source Type: clinical trials