The effect of vitamin K on prothrombin time in critically ill patients: an observational registry study

ConclusionIn critically ill patients with a PT-INR of 1.3 –1.9, the administration of vitamin K resulted in a slightly larger decrease of PT-INR 12–36 h after administration compared to controls. Future studies should focus on identifying which patient populations may benefit most from vitamin K administration as well as whether vitamin K could be a better alternative than plasma or prothrombin complex concentrate to improve PT-INR before non-emergent invasive procedures.
Source: Journal of Intensive Care - Category: Intensive Care Source Type: research