Lipocalin-2: a role in hepatic gluconeogenesis via AMP-activated protein kinase (AMPK)

ConclusionThe present study demonstrates that LCN2 regulates insulin sensitivity and glucose metabolism through inhibiting AMPK activity, and regulating FoxO1 and its downstream genes PEPCK/G6P, which regulate hepatic gluconeogenesis.

http://link.springer.com/10.1007/s40618-020-01494-0

Source: Journal of Endocrinological Investigation - January 9, 2021 Category: Endocrinology Source Type: research