Surgical Outcome and Histological Differences between Individuals with TGFBR1 and TGFBR2 Mutations in Loeys-Dietz Syndrome.

CONCLUSION: LDS patients with TGFBR2 mutations had higher grade of CMN than those of TGFBR1 mutations. In particular, in female patients with TGFBR2 mutations, AD after the initial surgery and reoperation were more frequent than those of other LDS patients.
PMID: 33408307 [PubMed - as supplied by publisher]

Source: Annals of Thoracic and Cardiovascular Surgery - January 6, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Seike Y, Matsuda H, Ishibashi-Ueda H, Morisaki H, Morisaki T, Minatoya K, Ogino H Tags: Ann Thorac Cardiovasc Surg Source Type: research