Echocardiographic and Biohumoral Characteristics in Patients With AL and TTR Amyloidosis at Diagnosis

ConclusionsOur data show that at time of first diagnosis, TTR patients have a more advanced amyloidotic involvement of the heart, despite less severe symptoms and biohumoral signs of heart failure. We can hypothesize that we observed different diseases at different stages. In fact, AL amyloidosis is a multiorgan disease with quick progression rate, that becomes rapidly symptomatic, whereas TTR amyloidosis might have a slow progression rate and might remain poorly symptomatic for a greater amount of time.

Source: Clinical Cardiology - February 2, 2015 Category: Cardiology Authors: Francesco Cappelli, Samuele Baldasseroni, Franco Bergesio, Stefano Perlini, Francesco Salinaro, Luigi Padeletti, Paola Attanà, Alessandro Paoletti Perini, Alberto Moggi Pignone, Elisa Grifoni, Alessia Fabbri, Niccolò Marchionni, Gian Franco Gensini, Fed Tags: Clinical Investigations Source Type: research