Appropriate Clinical Trial Registration is a Key to Transparent Reporting and Publication

What is the purpose of trial registration and why is it so important to the integrity of research? Clinical trial registration serves the following purposes. First, by pre-registering the trials, the primary outcome (why do the study) and method (how to do the study) get disclosed to the public. This makes certain biases unlikely to interfere with the interpretation of the results. Secondly, pre-registration prevents conscious or unconscious manipulation of the results. This protects the integrity of the study.
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Editorial Source Type: research