CytoDel announces successful intra-neuronal antibody delivery without a viral vector

(CytoDel Inc) Preclinical data published inScience Translational Medicine showed that post-symptomatic administration of Cyto-111 produced antidotal rescue in three animal species following a lethal botulism challenge. Study authors concluded, " atoxic BoNT derivatives can be harnessed to deliver therapeutic protein moieties to the neuronal cytoplasm where they bind and neutralize intracellular targets in experimental models. The generalizability of this platform might enable delivery of antibodies and other protein-based therapeutics to previously inaccessible intraneuronal targets. "
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news