Effect of Ocrelizumab in Blood Leukocytes of Patients With Primary Progressive MS

Conclusions
In PPMS, effector B-cell depletion changed T-cell response toward a low inflammatory profile, resulting in decreased sNfL levels.

Source: Neurology Neuroimmunology and Neuroinflammation - January 6, 2021 Category: Neurology Authors: Fernandez-Velasco, J. I., Kuhle, J., Monreal, E., Meca-Lallana, V., Meca-Lallana, J., Izquierdo, G., Gascon-Gimenez, F., Sainz de la Maza, S., Walo-Delgado, P. E., Maceski, A., Rodriguez-Martin, E., Roldan, E., Villarrubia, N., Saiz, A., Blanco, Y., Sanch Tags: All Demyelinating disease (CNS), Multiple sclerosis Article Source Type: research