Low MGMT digital expression is associated with a better outcome of IDH1 wildtype glioblastomas treated with temozolomide

ConclusionsMGMT mRNA levels evaluated by digital expression were associated with the outcome of TMZ-treated GBM patients. The combination ofMGMT methylation and mRNA expression may provide a more accurate prediction of TMZ response in GBM patients.
Source: Journal of Neuro-Oncology - Category: Cancer & Oncology Source Type: research