Hyperthermia induced disruption of mechanical balance leads to G1 arrest and senescence in cells.

This study elucidates the significant role of cellular traction, focal adhesions, and cytoskeletal networks in mitotic cell rounding and chromosomal misalignment. It also highlights the significance of HDAC6 in heat-evoked senile cellular responses. PMID: 33346336 [PubMed - as supplied by publisher]
Source: The Biochemical Journal - Category: Biochemistry Authors: Tags: Biochem J Source Type: research