Level of secreted HMGB1 correlates with severity of inflammation in chronic rhinosinusitis

ConclusionOur results showed that HMGB1 is secreted into the extracellular area space in the upper airway, and HMGB1 levels in nasal lavage fluid correlate with severity of inflammation, as assessed by the Lund‐Mackay staging system for chronic rhinosinusitis. These results provide evidence for HMGB1 as an inflammatory mediator associated with the severity of chronic rhinosinusitis. Level of EvidenceN/A. Laryngoscope, 2015

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1002%2Flary.25172

Source: The Laryngoscope - January 30, 2015 Category: ENT & OMF Authors: Hyun Jin Min, Su Jin Kim, Tae Hoon Kim, Hyo Jin Chung, Joo‐Heon Yoon, Chang‐Hoon Kim Tags: Allergy/Rhinology Source Type: research