A p38MAPK/MK2 signaling pathway leading to redox stress, cell death and ischemia/reperfusion injury

Conclusions:
These data highlight a novel and important mechanism for p38MAPK to cause IRI and suggest it as a potential therapeutic target for prevention of tissue injury.

Source: Cell Communication and Signaling - January 14, 2014 Category: Molecular Biology Authors: Muhammad AshrafMatthias EbnerChristoph WallnerMartina HallerSana KhalidHubert SchwelbergerKatarzyna KozielMarion EnthammerMartin HermannStephan SickingerAfschin SoleimanChristina StegerStephanie VallantRobert SucherGerald BrandacherPeter SanterDuska Dragu Source Type: research