Evidence of evolution towards left midventricular obstruction in severe Anderson –Fabry cardiomyopathy

ConclusionsFabry cardiomyopathy can evolve over time towards a midventricular obstructive form due to massive LVH in classically affected men with significant diagnostic delay and severe LVH before enzyme replacement therapy initiation. This newly described cardiac phenotype could represent an adverse outcome of the disease.

Source: ESC Heart Failure - November 19, 2020 Category: Cardiology Authors: Francesca Graziani, Rosa Lillo, Elena Panaioli, Gionata Spagnoletti, Maurizio Pieroni, Paolo Ferrazzi, Antonia Camporeale, Elena Verrecchia, Ludovico Luca Sicignano, Raffaele Manna, Filippo Crea Tags: Short Communication Source Type: research