Coinfection with Pseudomonas aeruginosa and Aspergillus fumigatus in cystic fibrosis

Conclusion A complex bi-directional relationship exists between P. aeruginosa and A. fumigatus, exhibiting both mutually antagonistic and cooperative facets. Cross-sectional data indicate a worsened disease state in coinfected patients; however, robust longitudinal studies are required to derive causality and to determine whether interspecies interaction contributes to disease progression.
Source: European Respiratory Review - Category: Respiratory Medicine Authors: Tags: CF and non-CF bronchiectasis Reviews Source Type: research