Sunitinib Produces Neuroprotective Effect Via Inhibiting Nitric Oxide Overproduction.

CONCLUSIONS: Sunitinib exerts its neuroprotective effects by inhibiting NO overproduction, possibly via the inhibition of nNOS activity and the decrease in nNOS expression. PMID: 24393200 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/24393200?dopt=Abstract

Source: CNS Neuroscience and Therapeutics - January 7, 2014 Category: Neuroscience Authors: Cui W, Zhang ZJ, Hu SQ, Mak SH, Xu DP, Choi CL, Wang YQ, Tsim WK, Lee MY, Rong JH, Han YF Tags: CNS Neurosci Ther Source Type: research