Development and evaluation of a serological test for diagnosis of COVID-19 with selected recombinant spike proteins

In conclusion, the eukaryotic expression spike proteins (rS1 and rS-RBD-mFc) are more suitable than the prokaryotic expression nucleocapsid proteins for serological diagnosis of SARS-CoV-2. The proposed GICA for detection of total antibodies could be a powerful complement to the current RNA tests for COVID-19.
Source: European Journal of Clinical Microbiology and Infectious Diseases - Category: Microbiology Source Type: research