Protrudin-deficient mice manifest depression-like behavior with abnormalities in activity, attention, and cued fear-conditioning

Protrudin is a protein that resides in the membrane of the endoplasmic reticulum and is highly expressed in the nervous system. Although mutations in the human protrudin gene (ZFYVE27, also known as SPG33) give r...

Source: Molecular Brain - November 10, 2020 Category: Neuroscience Authors: Michiko Shirane, Hirotaka Shoji, Yutaka Hashimoto, Hiroyuki Katagiri, Shizuka Kobayashi, Toshiya Manabe, Tsuyoshi Miyakawa and Keiichi I. Nakayama Tags: Research Source Type: research