The serotonin receptor 2A (HTR2A) rs6313 variant is associated with higher ongoing pain and signs of central sensitization in neuropathic pain patients

ConclusionsThe specific association of the rs6313 variant with pinprick hyperalgesia and increased levels of ongoing pain suggests that the HTR2A receptor might be an important modulator in the development of CS in neuropathic pain.

https://onlinelibrary.wiley.com/doi/abs/10.1002/ejp.1696?af=R

Source: European Journal of Pain - November 10, 2020 Category: Anesthesiology Authors: Juliane Sachau, Henrike Bruckmueller, Janne Gierthm ühlen, Walter Magerl, Denisa May, Andreas Binder, Julia Forstenpointner, Judith Koetting, Christoph Maier, Thomas R. Tölle, Rolf‐Detlef Treede, Achim Berthele, Amke Caliebe, Carolin Dies Tags: ORIGINAL ARTICLE Source Type: research