The selective blockade of metabotropic glutamate receptor-5 attenuates fat accumulation in an < em > in vitro < /em > model of benign steatosis

In conclusion, mGluR5 pharmacological blockade reduced fat accumulation in HepG2 cel ls incubated with O/P, probably by modulating the expression of SREBP-1 and PPAR-α.

https://www.ejh.it/index.php/ejh/article/view/3175

Source: European Journal of Histochemistry - October 19, 2020 Category: Biomedical Science Authors: Andrea Ferrigno, Clarissa Berardo, Laura Giuseppina Di Pasqua, Marta Cagna, Veronica Siciliano, Plinio Richelmi, Mariapia Vairetti Source Type: research

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