Prevalence of CBAVD in azoospermic men carrying pathogenic CFTR mutations ‐ Evaluated in a cohort of 639 non‐vasectomized azoospermic men

Discussion and conclusionsCBAVD was found in  ~ 44% of men with ΔF508/R117H mutations. The data may support that CFTR mutations might affect male fertility through other mechanisms than obstruction of the genital tract. For a practical, clinical purpose analysis for onlyΔF508,R117H andIVS8 ‐5T seems sufficient until further research shows anything else.

Source: Andrology - November 7, 2020 Category: Urology & Nephrology Authors: Jens Fedder, Mette W. J ørgensen, Birte Engvad Tags: ORIGINAL ARTICLE Source Type: research