SLy2 ‐deficiency promotes B‐1 cell immunity and triggers enhanced production of IgM and IgG2 antibodies against pneumococcal vaccine

ConclusionOur results reveal reinforced specific antibody responses towards pneumococcal polysaccharides and enhanced IgG2 secretion as a consequence of SLy2 deficiency, which could be relevant to the development of more efficient vaccines.

Source: Immunity, Inflammation and Disease - October 24, 2020 Category: Allergy & Immunology Authors: Jennifer Jaufmann, Leyla T ümen, Fee Schmitt, Daniel Schäll, Max Holleben, Sandra Beer‐Hammer Tags: ORIGINAL RESEARCH Source Type: research