Proton pump inhibitors and the risk of colorectal cancer: a systematic review and meta-analysis of observational studies

ConclusionsAlthough the present meta-analysis suggests a weak association between long-term use (> 5 years) of PPIs and CRC, there is not enough statistical power to refute or confirm an association between the use of PPIs and CRC. More high-quality prospective cohort studies are needed to assess this correlation.
Source: International Journal of Colorectal Disease - Category: Gastroenterology Source Type: research