Managing PFAPA (periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis) in children

AbstractPeriodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) is an uncommon, often misdiagnosed condition usually affecting children and resolving spontaneously before adolescence. While no long-term adverse effects are known, PFAPA is painful and tiring, causing significant school or work absence for the patient and family. Episodic fevers 3 –6 weeks apart that respond within hours to a single corticosteroid dose support the diagnosis. Daily colchicine usually extends the symptom-free interval.
Source: Drugs and Therapy Perspectives - Category: Drugs & Pharmacology Source Type: research