Colchicine: the good, the bad, the ugly, and how to minimise the risks - Stamp LK, Horsley C, Karu LT, Dalbeth N, Barclay M.
Colchicine has an important role in managing various conditions, including gout, familial Mediterranean fever, amyloidosis, Behcet's syndrome, recurrent pericarditis, and calcium pyrophosphate deposition disease. The adverse effect profile of colchicine is... (Source: SafetyLit)
Source: SafetyLit - December 3, 2023 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

Colchicum autumnale intoxications: experience of the Poisons Information Centre, Austria 2002-2018 - Arif T, Bicker W, P öchacker S, Kögler A, Gangl C, Holzer A.
This study aimed to assess the severity of poisoning based on readily available clinical laboratory parameters... (Source: SafetyLit)
Source: SafetyLit - November 6, 2023 Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news

No Benefit of Colchicine After Stroke, TIA: CHANCE-3 No Benefit of Colchicine After Stroke, TIA: CHANCE-3
The anti-inflammatory agent, started within 24 hours of acute ischemic stroke or TIA, did not reduce subsequent stroke or other vascular events at 90 days in the CHANCE-3 trial.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 26, 2023 Category: Consumer Health News Tags: Cardiology News Source Type: news

A Price Jump From Pennies to $20/Pill for the Same Drug
(MedPage Today) -- In June the U.S. FDA approved colchicine (Lodoco) as the first anti-inflammatory drug for the prevention of heart attacks and strokes among people with established heart disease or multiple risk factors. One recent review reported... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - October 12, 2023 Category: Cardiology Source Type: news

Adverse Events Compared for Gout Flare Prophylactic Drugs Adverse Events Compared for Gout Flare Prophylactic Drugs
Patients receiving prophylactic colchicine or NSAIDs with initiation of allopurinol for gout have more adverse events than those who receive no prophylaxis, but these events are rare overall.Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - October 6, 2023 Category: Drugs & Pharmacology Tags: Rheumatology News Source Type: news

Pediatric colchicine poisoning with survival after a "lethal" overdose: a case report - Barbaria W, Khamassi I, Fkili M.
Colchicine is a tricyclic alkaloid that has both medicinal and poisonous properties. Colchicine poisoning is a life-threatening condition with high mortality. a 13-year-old girl presented to our department with vomiting, abdominal pain, and fever. she appe... (Source: SafetyLit)
Source: SafetyLit - September 25, 2023 Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news

Colchicine Still Needed in Allopurinol Up-Titration Strategy Colchicine Still Needed in Allopurinol Up-Titration Strategy
Patients taking colchicine had fewer gout flares than did those taking placebo for the first 6 months, but the number of flares evened out between the two groups over a 12-month period.Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - September 11, 2023 Category: Drugs & Pharmacology Tags: Rheumatology News Source Type: news

No Reduction in AF After Noncardiac Surgery With Colchicine: COP-AF No Reduction in AF After Noncardiac Surgery With Colchicine: COP-AF
COP-AF trial results showed no significant reduction in co-primary endpoints of clinically important AF or myocardial injury after noncardiac thoracic surgery, although there were positive trends.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - August 27, 2023 Category: Cardiology Tags: Cardiology News Source Type: news

Colchicine Stumbles for Protecting the Heart From Thoracic Surgery
(MedPage Today) -- AMSTERDAM -- Anti-inflammatory colchicine (Lodoco) given perioperatively around major non-cardiac thoracic surgery did not cut atrial fibrillation (Afib) or myocardial injury complications, the COP-AF trial showed, although... (Source: MedPage Today Surgery)
Source: MedPage Today Surgery - August 26, 2023 Category: Surgery Source Type: news

Could Colchicine Replace Aspirin After PCI for ACS? Could Colchicine Replace Aspirin After PCI for ACS?
Aspirin is typically given after PCI for acute coronary syndrome but can lead to major bleeding. Colchicine appears to be safer and may be equally efficacious, pilot data suggest.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - August 17, 2023 Category: Cardiology Tags: Cardiology News Source Type: news

Low-Dose Colchicine for ASCVD: Your Questions Answered Low-Dose Colchicine for ASCVD: Your Questions Answered
Cardiologist Michelle O ' Donoghue asks Paul Ridker about the dos and don ' ts for the anti-inflammatory drug colchicine in patients with atherosclerotic cardiovascular disease.theheart.org on Medscape (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 8, 2023 Category: Consumer Health News Tags: Cardiology Commentary Source Type: news

Colchicine for Excess ASCVD Risk in IMIDs? Experts Weigh In Colchicine for Excess ASCVD Risk in IMIDs? Experts Weigh In
Experts assess the potential of colchicine 0.5 mg to treat residual risk for atherosclerotic cardiovascular disease (ASCVD) in patients with immune-mediated inflammatory diseases (IMIDs).MDedge News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - June 30, 2023 Category: Cardiology Tags: Rheumatology News Source Type: news

Colchicine vs Afib; Winter Spike in Cardiac Arrests; Cardiologist Stabbed at Home
(MedPage Today) -- The anti-inflammatory colchicine, recently approved for cardiovascular prevention (under the trade name Lodoco), appeared to offer protection from postoperative atrial fibrillation in a meta-analysis. (EP Europace) Scientists... (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - June 27, 2023 Category: Cardiology Source Type: news

Jun 23 2023 This Week in Cardiology Jun 23 2023 This Week in Cardiology
Starting HF meds during hospitalization for HF, Impella, testosterone, and colchicine are the topics John Mandrola, MD, discusses in this week ' s podcast.theheart.org on Medscape (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - June 23, 2023 Category: Cardiology Tags: Cardiology Commentary Source Type: news

Low-Dose Colchicine Approved for CVD: Now What? Low-Dose Colchicine Approved for CVD: Now What?
The FDA has given the new low dose of colchicine a broad indication for use in atherosclerotic cardiovascular disease, but how will the drug actually be used in clinical practice?Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - June 22, 2023 Category: Neurology Tags: Cardiology News Source Type: news