The Earlier the Better for Colchicine Post-MI: COLCOT The Earlier the Better for Colchicine Post-MI: COLCOT
One substudy supported in-hospital initiation of colchicine and a second offered clues as to who may respond or experience tell-tale GI events.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - September 9, 2020 Category: Cardiology Tags: Cardiology News Source Type: news

Colchicine overdose: a South African experience, a case report - Essame J, Grossberg S, Mahomed A.
Introduction Colchicine overdose is uncommon but is associated with a high mortality rate. It has a narrow therapeutic index and has been described to have a 100% mortality with ingestion of>0.8  mg/kg (Finkelstein et al., 2010; Herran-Monge et al., 2013... (Source: SafetyLit)
Source: SafetyLit - September 1, 2020 Category: International Medicine & Public Health Tags: Poisoning Source Type: news

LoDoCo2: Added Steam for Colchicine as Secondary Prevention LoDoCo2: Added Steam for Colchicine as Secondary Prevention
The benefits emerged early and continued to accrue through the trial, with no suggestion of attenuation during up to 5 years of treatment.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - September 1, 2020 Category: Internal Medicine Tags: Cardiology News Source Type: news

Common medicine used to treat gout found to prevent progression of coronary disease
(Harry Perkins Institute of Medical Research) A major clinical trial involving 5,500 patients in Australia and the Netherlands found heart attacks and the need for coronary stenting or bypass surgery reduced by 30% in patients taking low dose colchicine, an old and widely available drug commonly used to treat gout. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 31, 2020 Category: International Medicine & Public Health Source Type: news

Colchicine Promising in COVID-19 Treatment? Colchicine Promising in COVID-19 Treatment?
Colchicine, an anti-inflammatory drug used to treat gout and rheumatic disease, may be a promising treatment for COVID-19, a randomized, open-label trial suggests.Medscape Medical News (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - June 30, 2020 Category: Allergy & Immunology Tags: Cardiology News Source Type: news

Colchicine May Improve Time to Clinical Deterioration in COVID-19
FRIDAY, June 26, 2020 -- Hospitalized patients with COVID-19 receiving colchicine have significantly improved time to clinical deterioration, according to a study published online June 24 in JAMA Network Open. Spyridon G. Deftereos, M.D., Ph.D.,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 26, 2020 Category: Pharmaceuticals Source Type: news

Could an old gout drug help treat coronavirus? Study suggests colchicine can fight inflammation
A new study from the University of Athens in Greece found that 14% of coronavirus patients in a control group died compared to 1.8% in the group receiving colchicine, an old gout drug. (Source: the Mail online | Health)
Source: the Mail online | Health - June 25, 2020 Category: Consumer Health News Source Type: news

A 2000-year-old medicine might find its thunder amidst Covid scare
The trial involved 105 Greek patients hospitalised with Covid-19. The results suggest a significant clinical benefit from colchicine in patients who are hospitalised with Covid-19. Doctors in India say that the drug is commonly available in India and is also used in some heart conditions. (Source: The Economic Times)
Source: The Economic Times - June 25, 2020 Category: Consumer Health News Source Type: news

In Early Trial, an Ancient Drug, Colchicine, Shows Promise Against Severe COVID-19
WEDNESDAY, June 24, 2020 -- There's new evidence that a 2,000-year-old medicine might offer hope against a modern scourge: COVID-19. The medication, called colchicine, is an anti-inflammatory taken as a pill. It's long been prescribed for gout, a... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - June 24, 2020 Category: General Medicine Source Type: news

Effect of colchicine on biomarkers and clinical outcomes in patients hospitalized with COVID-19
(JAMA Network) This randomized clinical trial evaluates the effect of treatment with colchicine on cardiac and inflammatory biomarkers and clinical outcomes in patients hospitalized with COVID-19. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - June 24, 2020 Category: Infectious Diseases Source Type: news

Could an Ancient Drug Help Fight Severe COVID-19?
WEDNESDAY, April 22, 2020 -- As researchers hunt for ways to treat severe COVID-19 infections, a new trial will ask whether an old arthritis drug can prevent serious complications in the first place. The medication, called colchicine, is an oral... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - April 22, 2020 Category: General Medicine Source Type: news

Could Gout Drug Colchicine Help Fight Severe COVID-19?
WEDNESDAY, April 22, 2020 -- As researchers hunt for ways to treat severe COVID-19 infections, a new trial will ask whether an old arthritis drug can prevent serious complications in the first place. The medication, called colchicine, is an oral... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - April 22, 2020 Category: General Medicine Source Type: news

New trial will send drug to COVID-19 patients' home to see if it can prevent serious complications
A new international clinical trial will examine if colchicine, a drug most often used to treat gout, can can reduce rates of hospitalization and death caused by the novel coronavirus. (Source: the Mail online | Health)
Source: the Mail online | Health - April 21, 2020 Category: Consumer Health News Source Type: news

Adverse Events During Oral Colchicine Use Adverse Events During Oral Colchicine Use
Colchicine is commonly used in the treatment of inflammatory diseases, but what do we know about the potential adverse events associated with its use?Arthritis Research & Therapy (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - April 7, 2020 Category: Consumer Health News Tags: Rheumatology Journal Article Source Type: news

Could Colchicine Be the New Aspirin? Could Colchicine Be the New Aspirin?
Michel Zeitouni talks to Jean-Claude Tardif about the COLCOT series of clinical trials testing colchicine, an anti-inflammatory gout drug, for the prevention and treatment of cardiovascular disease.theheart.org on Medscape (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 27, 2020 Category: Consumer Health News Tags: Cardiology Expert Interview Source Type: news

What Is the Classic Clinical Presentation of Pericarditis?
Discussion The pericardium is a bi-layered membrane that envelops the heart and provides a barrier to prevent disease and also decreases friction as the heart moves. Pericarditis is the inflammation of pericardium. The incidence is underreported as asymptomatic or mild disease may go unrecognized. From hospitalized patient data, 0.2-5% of patients with various cardiac disease had pericarditis. An incidence rate for hospitalizations of 3.32 per 100,000 person years has been cited. Percarditis occurs more often in adolescent males. Treatment of the underlying cause or suspected cause is important, along with close monitorin...
Source: PediatricEducation.org - January 13, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Drug used to treat gout cuts odds of new heart attack, stroke in heart attack survivors
The inflammation-fighting drug colchicine, already a treatment for gout, dramatically reduces the odds of future cardiovascular problems in people who have just survived a heart attack, a large new study by a Montreal researcher has concluded. (Source: CBC | Health)
Source: CBC | Health - November 18, 2019 Category: Consumer Health News Tags: News/Health Source Type: news

Colchicine cuts odds of new heart attack, stroke in heart attack survivors
(Reuters Health) - The inflammation-fighting drug colchicine, already a treatment for gout, dramatically reduces the odds of future cardiovascular problems in people who have just survived a heart attack, a large new study has concluded. (Source: Reuters: Health)
Source: Reuters: Health - November 18, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

Cheap, Older Gout Drug Could Be a Lifesaver After Heart Attack
In the new trial, colchicine reduced by as much as 34% a heart attack survivor's combined risk of either dying from heart disease or having cardiac arrest, a heart attack, a stroke or angioplasty. (Source: WebMD Health)
Source: WebMD Health - November 18, 2019 Category: Consumer Health News Source Type: news

AHA: Risk for Ischemic CV Events Lower With Colchicine After MI
MONDAY, Nov. 18, 2019 -- Patients with recent myocardial infarction have a lower risk for ischemic cardiovascular events with colchicine versus placebo, according to a study published online Nov. 16 in the New England Journal of Medicine to coincide... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - November 18, 2019 Category: Pharmaceuticals Source Type: news

Colchicine Before PCI Cuts Inflammatory Markers but Not MACE Colchicine Before PCI Cuts Inflammatory Markers but Not MACE
Although colchicine did not significantly reduce major adverse cardiovascular events after PCI, the researchers are encouraged by significant decreases in markers of inflammation vs placebo.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - November 18, 2019 Category: Cardiology Tags: Cardiology News Source Type: news

Older Gout Drug Colchicine Could Be a Lifesaver After Heart Attack
SUNDAY, Nov. 17, 2019 -- A cheap drug that's been around for centuries as a gout treatment might also shield heart attack survivors from future heart crises, new trial results show. The drug, colchicine, is derived from a plant called the autumn... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - November 17, 2019 Category: General Medicine Source Type: news

COLCOT: Colchicine Shows Promise to Reduce Events After MI COLCOT: Colchicine Shows Promise to Reduce Events After MI
A widely available anti-inflammatory agent used to treat pericarditis and gout may have value in secondary prevention after myocardial infarction, new trial results suggest.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - November 16, 2019 Category: Cardiology Tags: Cardiology News Source Type: news

Rapid identification of Gloriosa superba and Colchicum autumnale by melting curve analysis: application to a suicide case involving massive ingestion of G. superba - Sakurada M, Yoshioka N, Kuse A, Nakagawa K, Morichika M, Takahashi M, Kondo T, Asano M, Ueno Y.
The plant species Gloriosa superba and Colchicum autumnale produce extremely poisonous colchicine as a major toxic metabolite. Almost all previous studies on colchicine poisoning have focused on drug analysis and clinical and pathological aspects. In this ... (Source: SafetyLit)
Source: SafetyLit - May 2, 2019 Category: International Medicine & Public Health Tags: Poisoning Source Type: news

Colchicine May Improve Obesity-Induced Inflammation
FRIDAY, April 12, 2019 -- Colchicine is safe and effective at improving obesity-associated inflammatory measures among adults with obesity and metabolic syndrome (MetS) without diabetes, according to a pilot study published online March 14 in... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - April 12, 2019 Category: Pharmaceuticals Source Type: news

10 New Drugs for Primary Care: Q1 2019
Highlights:  The first liquid solution of colchicine for prophylaxis of gout, the first generic version of Advair Diskus,® and 8 more new and approved drugs. (Source: ConsultantLive)
Source: ConsultantLive - April 11, 2019 Category: Internal Medicine Authors: Sydney Jennings Tags: ADHD Asthma COPD Depression Gout Headache and Migraine HIV AIDS Source Type: news

Gout treatment may help prevent obesity-related type 2 diabetes, suggests small NIH study
Colchicine may potentially reduce complications accompanying metabolic syndrome. (Source: National Institutes of Health (NIH) News Releases)
Source: National Institutes of Health (NIH) News Releases - April 2, 2019 Category: American Health Source Type: news

Gout treatment may help prevent obesity-related type 2 diabetes, suggests small NIH study
(NIH/Eunice Kennedy Shriver National Institute of Child Health and Human Development) The drug colchicine, used to treat the arthritic condition gout, could potentially reduce complications accompanying metabolic syndrome, a combination of high blood pressure, high blood sugar and other conditions that increase the risk of heart disease and type 2 diabetes, according to researchers at the National Institutes of Health. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - April 2, 2019 Category: International Medicine & Public Health Source Type: news

colchicine (Colcrys)
Title: colchicine (Colcrys)Category: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 3/26/2019 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - March 26, 2019 Category: Rheumatology Source Type: news

Epidemiology, toxicokinetics and biomarkers after self-poisoning with Gloriosa superba - Wijerathna TM, Gawarammana IB, Mohamed F, Dissanayaka DM, Dargan PI, Chathuranga U, Jayathilaka C, Buckley NA.
The objective of this study was to describe the epidemiology, toxicokinetics and selected ... (Source: SafetyLit)
Source: SafetyLit - March 24, 2019 Category: International Medicine & Public Health Tags: Poisoning Source Type: news

FDA OKs First Liquid Form of Gout Drug Colchicine (Gloperba) FDA OKs First Liquid Form of Gout Drug Colchicine (Gloperba)
Liquid colchicine for prophylaxis of gout flares in adults will be available in the US this summer.FDA Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - February 27, 2019 Category: Consumer Health News Tags: Rheumatology News Alert Source Type: news

FDA Approves Gloperba (colchicine) for Prophylaxis of Adult Gout Flares
WOBURN, Mass.--(BUSINESS WIRE)--February 26, 2019 ROMEG Therapeutics, an innovative drug development company focused on alternative formulations to better meet clinical and patient needs, today announced that the U.S. Food and Drug Administration... (Source: Drugs.com - New Drug Approvals)
Source: Drugs.com - New Drug Approvals - February 26, 2019 Category: Drugs & Pharmacology Source Type: news

Gloperba (Colchicine Oral Solution) - new on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - February 6, 2019 Category: Drugs & Pharmacology Source Type: news

Mitigare (Colchicine Capsules) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 17, 2018 Category: Drugs & Pharmacology Source Type: news

Colchicine extract suicidal lethal poisoning confirmation using high-resolution accurate mass spectrometry: a case study - Schreiber L, Morovi č M, Špacayová K, Halko R.
A case of suspected acute and lethal intoxication caused by colchicine has been reported. The woman was hospitalized after her suspicion of suicidal poisoning by a rare autumn crocus (Colchicum autumnale). Suspected colchicine poisoning was confirmed using... (Source: SafetyLit)
Source: SafetyLit - December 13, 2018 Category: International Medicine & Public Health Tags: Poisoning Source Type: news

Zydus Cadila gets USFDA nod for generic gout attacks drug
The company has received the tentative approval from the USFDA to market Colchicine tablets USP in the strength of 0.6 mg, Zydus Cadila said in a statement. (Source: The Economic Times Healthcare and Biotech News)
Source: The Economic Times Healthcare and Biotech News - October 18, 2018 Category: Pharmaceuticals Source Type: news

Canakinumab Efficacy Confirmed In Recurrent Fever Disorders Canakinumab Efficacy Confirmed In Recurrent Fever Disorders
Canakinumab controlled flares in colchicine-resistant familial Mediterranean fever, mevalonate kinase deficiency, and tumor necrosis factor receptor-associated periodic syndrome.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 23, 2018 Category: Consumer Health News Tags: Rheumatology News Source Type: news

Colcrys (Colchicine Tablets) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - March 6, 2018 Category: Drugs & Pharmacology Source Type: news

Severe hypertriglyceridemia and colchicine intoxication following suicide attempt - Lev S, Snyder D, Azran C, Zolotarsky V, Dahan A.
We report a case of an 18-year-old female who ingested 18 mg (~0.4 mg/kg) of colchicine in a suicide att... (Source: SafetyLit)
Source: SafetyLit - December 8, 2017 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news

Should Colchicine Join the Anti-Inflammatory Toolbox? Should Colchicine Join the Anti-Inflammatory Toolbox?
The commonly used drug was shown for the first time on serial CT imaging to modify coronary plaque morphology, but experts question whether these changes will translate into improved hard clinical events.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - November 7, 2017 Category: Consumer Health News Tags: Cardiology News Source Type: news

CardioBrief: Imaging Offers Insight Into Inflammation in CV Disease
(MedPage Today) -- Preliminary evidence that colchicine may reduce coronary plaque (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - October 19, 2017 Category: Cardiology Source Type: news

Probenecid and Colchicine (Probenecid and Colchicine) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 25, 2016 Category: Drugs & Pharmacology Source Type: news

IL-1 Blocking Agent Succeeds in Resistant FMF (CME/CE)
(MedPage Today) -- First randomized trial among colchicine-resistant patients (Source: MedPage Today Primary Care)
Source: MedPage Today Primary Care - November 28, 2016 Category: Primary Care Source Type: news

Colchicine (Colchicine) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - August 31, 2016 Category: Drugs & Pharmacology Source Type: news

Pyridine based antitumor compounds acting at the colchicine site
(Bentham Science Publishers) Tubulin inhibitors are among the most successful anti-cancer, anti-parasitic and herbicidal agents. Lessons from the achievements and failures have been extracted and future perspectives delineated. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - June 30, 2016 Category: Biology Source Type: news

colchicine, Colcrys
Title: colchicine, ColcrysCategory: MedicationsCreated: 12/31/1997 12:00:00 AMLast Editorial Review: 6/29/2016 12:00:00 AM (Source: MedicineNet Arthritis General)
Source: MedicineNet Arthritis General - June 29, 2016 Category: Rheumatology Source Type: news

Case report: a rare case of attempted homicide with Gloriosa superba seeds - Kande Vidanalage CJ, Ekanayeka R, Wijewardane DK.
BACKGROUND: Gloriosa superba, well known as the glory lily or superb lily, is a tropical climbing plant that features an exotic red flower. The plant is poisonous because of high concentrations of colchicine in all parts of the plant. It is commercially gr... (Source: SafetyLit)
Source: SafetyLit - June 25, 2016 Category: Global & Universal Tags: Poisoning Source Type: news

Mitigare (Colchicine Capsules) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - April 25, 2016 Category: Drugs & Pharmacology Source Type: news

Colchicine-induced rhabdomyolysis: an autopsy case - Arslan MN, Özgün A, Daş T, Kumru D, Sam B, Koç S.
Colchicine is derived from Colchicum autumnale and Gloriosa superba and is used to treat acute gout and familial Mediterranean fever (FMF). Musculoskeletal adverse effects range from myopathy to rhabdomyolysis. An 18-year-old woman, with a 2-year history o... (Source: SafetyLit)
Source: SafetyLit - April 11, 2016 Category: Global & Universal Tags: Alcohol and Other Drugs Source Type: news

Rely on Colchicine for FMF, Experts Say (CME/CE)
(MedPage Today) -- New guideline for treatment of familial Mediterranean fever (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - January 27, 2016 Category: Pediatrics Source Type: news