Drug vignettes: Colchicine, CEBM
Colchicine is an alkaloid present in all parts of the autumn crocus, Colchicum autumnale. It has been used therapeutically since the first half of the 19th century. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - February 4, 2021 Category: Consumer Health News Source Type: news
The Sooner, the Better: Anti-inflammation in Acute MI The Sooner, the Better: Anti-inflammation in Acute MI
Should we be using colchicine in the very early phase of ACS to reduce major coronary events? This commentary explores the benefits and possible caveats.European Heart Journal (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 25, 2021 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news
ColCORONA: Colchicine Reduces Complications in Outpatient COVID-19 ColCORONA: Colchicine Reduces Complications in Outpatient COVID-19
The primary endpoint was not significant in the overall population, but in those with PCR-confirmed COVID, treatment reduced hospitalization, need for ventilation, and death, top-line results show.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
Source: Medscape Hematology-Oncology Headlines - January 25, 2021 Category: Cancer & Oncology Tags: Cardiology News Source Type: news
Quebec researchers say they have found an effective drug to fight COVID-19
A team of researchers from the Montreal Heart Institute believes they have found an effective weapon against COVID-19: colchicine, an... (Source: Reuters: Health)
Source: Reuters: Health - January 24, 2021 Category: Consumer Health News Source Type: news
Drug treatments for covid-19: living systematic review and network meta-analysis (update), BMJ
Updated review includes results for new interventions (azithromycin, colchicine, interferons, rhG-CSF, tocilizumab) and evidence remdesivir may not reduce mortality or time to symptom resolution; glucocorticoids probably reduce length of ICU stay and increase ventilator-free days BMJ2020; 370 doi: 2 External 0 0 0 https://doi.org/10.1136/bmj.m2980 false https://doi.org/10.1136/bmj.m2980 true false%> (Published 30 July 2020). Cite this as: BMJ 2020;370:m2980. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - December 21, 2020 Category: Consumer Health News Source Type: news
Colchicine a Case Study for What's Wrong With US Drug Pricing Colchicine a Case Study for What's Wrong With US Drug Pricing
A Medicare/Medicaid analysis shows a prolonged public-spending burden, despite generics available outside the United States for pennies a pill. Meanwhile, use widens from gout to MI, even COVID-19.Medscape Medical News (Source: Medscape Pharmacist Headlines)
Source: Medscape Pharmacist Headlines - December 2, 2020 Category: Drugs & Pharmacology Tags: Cardiology News Source Type: news
Gout drug Colchicine to be tested as COVID-19 treatment in UK trial, Reuters
The RECOVERY trial, which is world ' s largest clinical trial of treatments for patients hospitalised with COVID-19, will randomly allocate at least 2,500 patients recruited to receive the anti-inflammatory colchicine, as inflammation is considered to play a major role in COVID-19. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - November 30, 2020 Category: Consumer Health News Source Type: news
Accidental poisoning with autumn crocus (Colchicum autumnale): a case series - Razinger G, Kozelj G, Gorjup V, Grenc D, Brvar M.
In this study, we retros... (Source: SafetyLit)
Source: SafetyLit - November 11, 2020 Category: International Medicine & Public Health Tags: Home and Consumer Product Safety Source Type: news
ESC 2020 Highlights: Drugs Old and New ESC 2020 Highlights: Drugs Old and New
Top trials from the virtual ESC 2020 featured old drugs such as aspirin and colchicine as well as the new SGLT2 inhibitors.theheart.org on Medscape (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - October 12, 2020 Category: Cardiology Tags: Cardiology Commentary Source Type: news
The Earlier the Better for Colchicine Post-MI: COLCOT The Earlier the Better for Colchicine Post-MI: COLCOT
One substudy supported in-hospital initiation of colchicine and a second offered clues as to who may respond or experience tell-tale GI events.Medscape Medical News (Source: Medscape Cardiology Headlines)
Source: Medscape Cardiology Headlines - September 9, 2020 Category: Cardiology Tags: Cardiology News Source Type: news
Colchicine overdose: a South African experience, a case report - Essame J, Grossberg S, Mahomed A.
Introduction
Colchicine overdose is uncommon but is associated with a high mortality rate. It has a narrow therapeutic index and has been described to have a 100% mortality with ingestion of>0.8 mg/kg (Finkelstein et al., 2010; Herran-Monge et al., 2013... (Source: SafetyLit)
Source: SafetyLit - September 1, 2020 Category: International Medicine & Public Health Tags: Poisoning Source Type: news
LoDoCo2: Added Steam for Colchicine as Secondary Prevention LoDoCo2: Added Steam for Colchicine as Secondary Prevention
The benefits emerged early and continued to accrue through the trial, with no suggestion of attenuation during up to 5 years of treatment.Medscape Medical News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - September 1, 2020 Category: Internal Medicine Tags: Cardiology News Source Type: news
Common medicine used to treat gout found to prevent progression of coronary disease
(Harry Perkins Institute of Medical Research) A major clinical trial involving 5,500 patients in Australia and the Netherlands found heart attacks and the need for coronary stenting or bypass surgery reduced by 30% in patients taking low dose colchicine, an old and widely available drug commonly used to treat gout. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 31, 2020 Category: International Medicine & Public Health Source Type: news
Colchicine Promising in COVID-19 Treatment? Colchicine Promising in COVID-19 Treatment?
Colchicine, an anti-inflammatory drug used to treat gout and rheumatic disease, may be a promising treatment for COVID-19, a randomized, open-label trial suggests.Medscape Medical News (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - June 30, 2020 Category: Allergy & Immunology Tags: Cardiology News Source Type: news
Colchicine May Improve Time to Clinical Deterioration in COVID-19
FRIDAY, June 26, 2020 -- Hospitalized patients with COVID-19 receiving colchicine have significantly improved time to clinical deterioration, according to a study published online June 24 in JAMA Network Open.
Spyridon G. Deftereos, M.D., Ph.D.,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - June 26, 2020 Category: Pharmaceuticals Source Type: news
