Prednisolone Versus Colchicine for Acute Gout in Primary Care: statistical analysis plan for the pragmatic, multicenter, randomized, and double-blinded COPAGO non-inferiority trial
DiscussionThe trial will provide evidence from a direct comparison of colchicine and prednisolone regarding their efficacy of pain reduction in acute gout patients of primary care and to indicate possible safety signals.Trial registrationClinicalTrials.gov Identifier: NCT05698680 first posted on January 26, 2023 (retrospectively registered). (Source: Trials)
Source: Trials - April 3, 2024 Category: Research Source Type: clinical trials
Effect of Colchicine on Progression of Known Coronary Atherosclerosis in Patients With Stable Coronary Artery Disease
Conditions: Coronary Artery Disease Interventions: Drug: Colchicine 0.5 MG Sponsors: Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 2, 2024 Category: Research Source Type: clinical trials
Randomized Controlled Trial in Patients on Long-term Colchicine With Colchicine-resistant Familial Mediterranean Fever (FMF) to Evaluate the Efficacy of On-demand Anakinra Treatment for Painful Attacks in Patients Who Refuse Continuous Daily Therapy
Conditions: FMF Interventions: Drug: ANAKINRA Sponsors: Assistance Publique - H ôpitaux de Paris Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 29, 2024 Category: Research Source Type: clinical trials
Colchicine Versus Beta-blockers, Angiotensin-converting Enzyme Inhibitors, and Statins for Prevention of Chemotherapy-Induced Cardiomyopathy
Conditions: Chemotherapy Induced Systolic Dysfunction Interventions: Drug: Carvedilol; Drug: Ramipril; Drug: Rosuvastatin; Drug: Colchicine; Drug: Placebo Sponsors: Arab Contractors Medical Centre Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 11, 2024 Category: Research Source Type: clinical trials
Colchicine in Acutely Decompensated HFREF
Conditions: Heart Failure; Decompensated Heart Failure; Heart Failure With Reduced Ejection Fraction Interventions: Drug: Colchicine 0.6 mg; Drug: Control/Placebo group Sponsors: University of Virginia Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 29, 2024 Category: Research Source Type: clinical trials
Aggressive Risk-Prevention Therapies for Coronary Atherosclerotic Plaque (ART-CAP)
Conditions: Coronary Artery Disease; Atherosclerosis, Coronary Interventions: Drug: Statin; Drug: Aspirin tablet; Drug: Nexlizet; Drug: LEQVIO; Drug: Vascepa; Drug: Jardiance; Drug: Colchicine Sponsors: University of Louisville Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials
Colchicine in Patients at Cardiac Risk Undergoing Major Non-Cardiac Surgery
Conditions: Cardiovascular Diseases; Cardiovascular Complication; Perioperative Complication; Myocardial Infarction Interventions: Drug: Colchicine; Drug: Placebo Sponsors: Cantonal Hospital of St. Gallen Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 26, 2024 Category: Research Source Type: clinical trials
A Study of SSGJ-613 in Gout Subjects Initiating Urate-Lowering Treatment.
Conditions: Gout Arthritis Interventions: Drug: Recombinant Anti-IL-1 β Humanized Monoclonal Antibody Injection 100 mg; Drug: Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection 200 mg; Drug: Colchicine 0.5 mg Sponsors: Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 21, 2024 Category: Research Source Type: clinical trials
Treatment of ACuTe Coronary Syndromes With Low-dose colchICine
Conditions: Acute Coronary Syndrome; Unstable Angina; ST Elevation Myocardial Infarction; Non ST Segment Elevation Myocardial Infarction; Colchicine Interventions: Drug: Colchicine Pill; Drug: Placebo Sponsors: Beijing Anzhen Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 22, 2024 Category: Research Source Type: clinical trials
Reversing Microvascular Dysfunction in Heart Failure With Preserved Ejection Fraction
Conditions: Heart Failure With Preserved Ejection Fraction; Microvascular Coronary Artery Disease Interventions: Drug: Colchicine 0.5 MG Sponsors: Montreal Heart Institute Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 22, 2024 Category: Research Source Type: clinical trials
A Mechanistic Clinical Trial of Colchicine in Patients Undergoing Femoral Endarterectomy
Conditions: Peripheral Artery Disease Interventions: Drug: Colchicine; Drug: Placebo Sponsors: University of Pennsylvania; Doris Duke Charitable Foundation Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 18, 2024 Category: Research Source Type: clinical trials
Inflammation REduction to Prevent cArdiovascular Injury in Renal Disease (REPAIR)
Conditions: Chronic Kidney Diseases; Renal Failure Interventions: Drug: Colchicine Sponsors: Hamilton Health Sciences Corporation; Hamilton Academic Health Sciences Organization; St. Joseph ' s Health Care London Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 12, 2024 Category: Research Source Type: clinical trials
CMP-MYTHiC Trial and Registry - CardioMyoPathy With MYocarditis THerapy With Colchicine
Conditions: Cardiomyopathies; Myocarditis; Inflammatory Cardiomyopathy; Heart Failure; Ventricular Arrythmia Interventions: Drug: Colchicine; Other: Placebo Sponsors: Niguarda Hospital; European Union; Ministry of Health, Italy; Mario Negri Institute for Pharmacological Research; University of Milano Bicocca Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 6, 2023 Category: Research Source Type: clinical trials
Withdrawal of Colchicine in Beh çet Syndrome
Conditions: Beh çet ' s Syndrome Interventions: Drug: Colchicine Sponsors: Istanbul University - Cerrahpasa (IUC) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 24, 2023 Category: Research Source Type: clinical trials
Efficacy of LoDoCo in Improving Exercise Capacity Among Patients With HFpEF and Inflammation
Conditions: Heart Failure; Inflammation Interventions: Drug: Low Dose Colchicine; Drug: Placebo Sponsors: University of Texas Southwestern Medical Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 13, 2023 Category: Research Source Type: clinical trials
