Double Heterozygous Mutations in the BRCA2 and ATM Genes: A Case Report and Review of the Literature

Conclusion: Multiple primary malignant neoplasms can be encountered more frequently in DH pathogenic variant carriers, and the diagnosis of malignancies can be made at an earlier age through surveillance guided by genetic testing. In this rare case, more patient studies are needed to determine the contribution of DH inBRCA2 andATM genes to the phenotype.Breast Care

https://www.karger.com/Article/FullText/511430

Source: Breast Care - October 29, 2020 Category: Cancer & Oncology Source Type: research

Double Heterozygous Mutations in the < b > < i > BRCA2 < /i > < /b > and < b > < i > ATM < /i > < /b > Genes: A Case Report and Review of the Literature