Associations between physical activity, sedentary behavior, and urinary oxidized guanine in colorectal cancer patients: results from the ColoCare Study

Applied Physiology, Nutrition, and Metabolism, Ahead of Print. To determine associations between physical activity (PA), sedentary behavior (SB), and oxidative stress in colorectal cancer patients, ColoCare Study participants in Germany wore an accelerometer 6 and/or 12 months after surgery. Spearman partial correlations were used to assess associations between PA and urinary concentrations of oxidized guanine, a validated marker of oxidative stress. There were no significant associations between PA or SB and oxidized guanine in n = 76 measurements (ng/mg creatinine; r = 0.03, p = 0.76 for PA, r = –0.05, p = 0.69 for SB). Novelty Objectively measured PA was not associated with a marker of oxidative stress in colorectal cancer patients.

Source: Applied Physiology, Nutrition, and Metabolism - June 22, 2020 Category: Physiology Authors: Richard Viskochil Biljana Gigic Tengda Lin Stephanie Skender J ürgen Böhm Petra Schrotz-King Karen Steindorf Robert Owen Jane C. Figueiredo Christopher I. Li Erin M. Siegel Sheetal Hardikar David Shibata Adetunji T. Toriola Martin Schneider Alexis Ulric Source Type: research