Differentially expressed miR-152, a potential biomarker for in-stent restenosis (ISR) in peripheral blood mononuclear cells (PBMCs) of coronary artery disease (CAD) patients

ISR remains the most daunting challenge of current treatments of CAD. MicroRNAs (miRNAs) are prominent regulators of key pathological processes leading to restenosis are being used as diagnostic tools in different studies. miR-152 and miR-148a are implicated to contribute in the putative intracellular mechanisms of ISR. The aim of present study was to investigate the potential early stage diagnostic role of miR-152 and miR-148a expression levels for ISR in PBMCs of patients underwent stent implantation.
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - Category: Nutrition Authors: Source Type: research