Ciliary neurotrophic factor (CNTF) and its receptor (CNTFR α) signal through MAPK/ERK pathway in human prostate tissues: a morphological and biomolecular study

In conclusion, we suggest that CNTF could be considered as key molecule to maintenance epithelium homeostasisvia pERK downregulation by an autocrine mechanism. Further CNTF studies in prostate cancer could be useful to verify the potential role of this cytokine in carcinogenesis.
Source: European Journal of Histochemistry - Category: Biomedical Science Authors: Source Type: research