17.3 children with satb2-associated syndrome have increased emotional, behavior, and sleep disturbances

Special AT-rich sequence-binding protein 2 (SATB2)-associated syndrome (SAS) occurs due to disruptions of the SATB2 gene on chromosome 2. The common manifestations of SAS include neurodevelopmental delays, intellectual disability, behavioral problems, impaired speech, palate abnormalities, and teeth anomalies. A retrospective cohort study was conducted on children with SAS focusing on behavior and sleep disturbances. We aimed to explore if there were differences between this cohort and the normative sample.

Source: Journal of the American Academy of Child and Adolescent Psychiatry - October 1, 2020 Category: Psychiatry Authors: Elaine Leo, Nihit Kumar, Srinivasa B. Gokarakonda, Aisling R. Caffrey, Yuri A. Zarate Source Type: research