The First Unprovoked Seizure in Typically Developing Children: A Real-Life Setting in Southern Brazil.

The First Unprovoked Seizure in Typically Developing Children: A Real-Life Setting in Southern Brazil.
Clin EEG Neurosci. 2020 Oct 13;:1550059420965391
Authors: de Rezende Machado M, Bruck I, de Paola L, Cat MNL, Antoniuk SA, Silvado CES
Abstract
AIM: To describe the first unprovoked seizure in typically developing children, its clinical characteristics, recurrence rate, and possible risk factors in a real-life setting in Southern Brazil.
METHOD: In this retrospective cohort study, medical records of typically developing children aged 28 days to 14 years who had a first unprovoked seizure in a single tertiary care center were reviewed, in a 10-year period (2006-2016).
RESULTS: Seventy-four children were included, 41 males and 33 females. The most frequent age group of the first seizure was 5 to 10 years and seizure main type was focal (50%). Most seizures occurred while children were awake (70%). All patients underwent an electroencephalogram (EEG), which was normal in 44.6%. Neuroimaging was performed in 81%, in 2 cases the etiology was considered structural, the remaining was classified as unknown. Median follow-up period was 32.5 months. Seizure recurrence rate was 56.7% and age younger than 5 years was a possible risk factor.
INTERPRETATION: In the subpopulation of Brazilian typically developing children with a first unprovoked epileptic seizure there is a high recurrence rate. An abnormal EEG was a common...

Source: Clinical EEG and Neuroscience - October 13, 2020 Category: Neuroscience Authors: de Rezende Machado M, Bruck I, de Paola L, Cat MNL, Antoniuk SA, Silvado CES Tags: Clin EEG Neurosci Source Type: research