Interaction Between the 5-Hydroxytryptamine Transporter-Linked Polymorphic Region (5-HTTLPR) and Negative Life Events in Adolescent Heavy Drinking.

CONCLUSIONS: Using large prospective data, it appears that there is no evidence for 5-HTTLPR-moderated drinking following experience of negative life events and no support for 5-HTTLPR-moderated selection to negative life events among mid/late adolescents. This finding may inform developmental patterns in gene and environment interaction effects by showing that the effects are less pronounced in mid/late adolescence than in early adolescence. PMID: 33028469 [PubMed - in process]
Source: Journal of Studies on Alcohol and Drugs - Category: Addiction Tags: J Stud Alcohol Drugs Source Type: research