Design, Fabrication & Characterization of Graft Co-Polymer Assisted Ocular Insert: A State of Art in Reducing Post-Operative Pain.

Conclusion: It was concluded that the ocular inserts of the poorly soluble nepafenac developed using a graft-co-polymer enhanced the solubility and utilization of the drug for a prolonged period. Highlights:The use of graft Co-Polymer enhanced the solubility of Nepafenac and assisted in the design of ocular insert formulation.The problem of less contact time associated with eye drops is overcome by the novel formulation of Insert.The formulation remains in contact for longer period of time and hence provide enhanced duration of action and maximum drug utilization.It is biocompatible & bio erodible in nature. PMID: 33026260 [PubMed - as supplied by publisher]
Source: Drug Development and Industrial Pharmacy - Category: Drugs & Pharmacology Tags: Drug Dev Ind Pharm Source Type: research