The evolution of parkinsonism in primary progressive apraxia of speech: A 6-year longitudinal study

Primary progressive apraxia of speech (PPAOS) is a neurodegenerative syndrome in which patients present with an isolated motor speech disorder. Some PPAOS patients develop parkinsonism and other features of progressive supranuclear palsy (PSP) and/or corticobasal syndrome (CBS) over time. We aimed to assess the evolution of parkinsonian characteristics in PPAOS patients who had been followed yearly for at least six years.

Source: Parkinsonism and Related Disorders - October 6, 2020 Category: Neurology Authors: Zeynep Idil Seckin, Joseph R. Duffy, Edythe A. Strand, Heather M. Clark, Rene L. Utianski, Mary M. Machulda, Hugo Botha, Farwa Ali, Nha Trang Thu Pham, Val J. Lowe, Jennifer L. Whitwell, Keith A. Josephs Source Type: research