Enigma Biomedical inks deal to develop tau PET biomarkers
Enigma Biomedical Group USA (EBG-USA) has signed an exclusive agreement to commercialize AbbVie’s tau PET imaging biomarkers for use in patients with suspected neurodegenerative disease. Under the agreement, EBG-USA and AbbVie will collaborate with EBG-USA’s academic and pharmaceutical partner network to validate preclinical and clinical PET ligands during an initial evaluation period. If the evaluations are favorable, EBG-USA has the option to negotiate an exclusive license agreement with AbbVie for the PET ligands. Misfolded tau protein in the brain is a common feature of several neurodegenerative diseases, includi...
Source: AuntMinnie.com Headlines - January 24, 2024 Category: Radiology Authors: AuntMinnie.com staff writers Tags: Industry News Subspecialties Nuclear Radiology Source Type: news

Benzodiazepines Tied to Worse Outcomes in Progressive Supranuclear Palsy
(MedPage Today) -- People with progressive supranuclear palsy (PSP) who were prescribed benzodiazepine derivatives had a faster decline in PSP Rating Scale (PSPRS) scores than those who didn't have benzodiazepines, a post hoc analysis showed.... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - January 24, 2024 Category: Neurology Source Type: news

Researchers discover new molecular drug targets for progressive neurological disorder
There is no cure for progressive supranuclear palsy (PSP), a brain disorder marked by walking and balance difficulties. Its symptoms also mimic Parkinson's disease and dementia. The condition leads to rapid, progressive decline and death. In a new paper published in Nature Communications, Mayo researchers and collaborators outline new therapeutic targets that may lead to potential future treatments for PSP, as well as Alzheimer's disease and related disorders. People with PSP usually are diagnosed in their late 60s and 70s.… (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - November 3, 2023 Category: Databases & Libraries Source Type: news

What is progressive supranuclear palsy? Democrat Congresswoman Jennifer Wexton diagnosed with rare disease described as 'Parkinson's on steroids'
Rep Jennifer Wexton from Virginia (pictured) announced Monday she had been diagnosed with a rare neurological condition called progressive supranuclear palsy and will not seek reelection. (Source: the Mail online | Health)
Source: the Mail online | Health - September 19, 2023 Category: Consumer Health News Source Type: news

What Is Progressive Supranuclear Palsy? Lawmaker Calls Her Rare Neurological Disorder ‘Parkinson’s On Steroids.’
The representative from Virginia was first diagnosed with Parkinson ’s disease, which is much more common and affects patients similarly to supranuclear palsy. (Source: Forbes.com Healthcare News)
Source: Forbes.com Healthcare News - September 18, 2023 Category: Pharmaceuticals Authors: Mary Whitfill Roeloffs, Forbes Staff Tags: Business /business Innovation /innovation Healthcare /healthcare Breaking breaking-news topline Source Type: news

Virginia Rep. Wexton will not seek reelection, citing new diagnosis
Rep. Jennifer Wexton (D-Va.) announced on Monday that she will not seek reelection after receiving an updated, more serious diagnosis of progressive supranuclear palsy. Wexton revealed in April that she'd been diagnosed with Parkinson's Disease, saying at the time that she hoped to continue…#jenniferwexton #wexton #psp (Source: Reuters: Health)
Source: Reuters: Health - September 18, 2023 Category: Consumer Health News Source Type: news

Clinical correlates of fear of falling in progressive supranuclear palsy and multiple system atrophy - Mart ínez-Villota VA, Terroba-Chambi C, Castillo-Torres SA, Rossi M, Merello M.
BACKGROUND: Clinical correlates of fear of falling (FoF) are scarcely studied in patients with Progressive Supranuclear Palsy (PSP) and Multiple System Atrophy (MSA). OBJECTIVE: To evaluate the clinical correlates of FoF in PSP and MSA. MET... (Source: SafetyLit)
Source: SafetyLit - May 18, 2023 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Scott Satin, ‘Funny You Should Ask’ and ‘Most Outrageous Moments’ Producer, Dies at 64
Scott Satin, a longtime producer for shows such as Funny You Should Ask and Most Outrageous Moments, has died. He was 64. The Hollywood Reporter learned Satin died on Thursday following a years-long battle with progressive supranuclear palsy. Progressive supranuclear palsy is a rare…#scottsatin #funnyyoushouldask #hollywood #hollywoodsquares #byronallenshow #gongshow #meetmyfolks #marrymydad #superhero #allenmediagroup (Source: Reuters: Health)
Source: Reuters: Health - February 12, 2023 Category: Consumer Health News Source Type: news

Science Saturday: In neurodegenerative diseases, Mayo Clinic research finds shared gene patterns, widespread damage
Damage to brain cells in two separate neurodegenerative diseases — Alzheimer's disease and progressive supranuclear palsy — is not limited to specific parts of the brain and these diseases share a pattern of gene alterations within the brain, according to researchers at Mayo Clinic, the University of Florida and other collaborating organizations. The research ers say this finding suggests the neurodegenerative diseases may have the same underlying disease links. The finding, which is published in The Journal… (Source: Mayo Clinic Research News)
Source: Mayo Clinic Research News - May 28, 2022 Category: Research Source Type: news

Psychometric properties of the Beck Depression Inventory-II in progressive supranuclear palsy - Cuoco S, Cappiello A, Abate F, Tepedino MF, Erro R, Volpe G, Pellecchia MT, Barone P, Picillo M.
OBJECTIVES: Depression is one of the most common neuropsychiatric symptoms in progressive supranuclear palsy (PSP). Yet, few studies have examined the ability of available instruments to detect depressive symptoms in PSP. Aims of the present study were to ... (Source: SafetyLit)
Source: SafetyLit - September 12, 2021 Category: International Medicine & Public Health Tags: Research Methods, Surveillance and Codes, Models Source Type: news

Suicidal and death ideation in patients with progressive supranuclear palsy and corticobasal syndrome - Ou R, Wei Q, Hou Y, Zhang L, Liu K, Xu X, Gu X, Lin J, Jiang Z, Liu J, Song W, Cao B, Shang H.
This study aimed to explore the prevalence and clinical correlates of suicidal and death ideation (SDI) in patients with Progre... (Source: SafetyLit)
Source: SafetyLit - August 14, 2020 Category: International Medicine & Public Health Tags: Suicide and Self-Harm Source Type: news

Falls in progressive supranuclear palsy - Brown FS, Rowe JB, Passamonti L, Rittman T.
BACKGROUND: Despite falls being an almost universal clinical feature and central to the presentation and diagnostic criteria of progressive supranuclear palsy, our understanding of falls is surprisingly limited and there are few effective treatment options... (Source: SafetyLit)
Source: SafetyLit - January 27, 2020 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

Negative Phase 2 Trial Data Ends Development of PSP Drug Negative Phase 2 Trial Data Ends Development of PSP Drug
Phase 2 trial results show gosuranemab did not meet primary or key secondary endpoints in patients with progressive supranuclear palsy, leading to discontinuation of the drug ' s development for PSP.Medscape Medical News (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - December 13, 2019 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

The Falls and Frustrations of Progressive Supranuclear Palsy The Falls and Frustrations of Progressive Supranuclear Palsy
PSP is a rare neurogenerative disorder that is increasingly appreciated among neurologists. Yet effective treatments remain elusive.Medscape Neurology (Source: Medscape Neurology and Neurosurgery Headlines)
Source: Medscape Neurology and Neurosurgery Headlines - November 25, 2019 Category: Neurology Tags: Neurology & Neurosurgery Commentary Source Type: news

RightCare Progressive Neurological Conditions Toolkit
This toolkit will support systems to understand the priorities in care for people living with various progressive neurological conditions including multiple sclerosis (MS), motor neurone disease (MND), Parkinson ' s and the atypical Parkinsonism ' s of multiple system atrophy (MSA), progressive supranuclear palsy (PSP) and coticobasal degeneration (CBD). It provides the opportunity to assess and benchmark current systems to find opportunities for improvement. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - October 17, 2019 Category: Consumer Health News Source Type: news