Maternal Anxiety and Depression during Late Pregnancy and Newborn Brain White Matter Development PEDIATRICS

BACKGROUND AND PURPOSE: Anxiety and depression during pregnancy have been associated with an increased risk of adverse neurodevelopmental outcomes in offspring. We aimed to study the in utero effects of maternal anxiety and depression on early brain development. MATERIALS AND METHODS: Pregnant women were recruited at ~36 weeks of gestation for this prospective study. They were assessed for anxiety symptoms by the State-Trait Anxiety Inventory and for depression symptoms by the Beck Depression Inventory, 2nd Edition. After delivery, infant underwent an MR imaging examination of the brain without sedation, including DTI, for evaluation of white matter (WM) development. Infant fractional anisotropy values, a putative marker of WM integrity, were correlated with the mothers’ State-Trait Anxiety Inventory and Beck Depression Inventory scores by using both tract-based spatial statistics and ROI methods. RESULTS: Thirty-four infants were included in this study. Both maternal State-Anxiety and Trait-Anxiety scores negatively correlated (P
Source: American Journal of Neuroradiology - Category: Radiology Authors: Tags: PEDIATRICS Source Type: research

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CONCLUSION: Our findings suggest that interpersonal emotional regulation strategies impact the association of maternal emotional regulation strategies and maternal emotional wellbeing. PMID: 33012169 [PubMed - as supplied by publisher]
Source: Journal of Reproductive and Infant Psychology - Category: Psychiatry & Psychology Tags: J Reprod Infant Psychol Source Type: research
laborators in Research) Anxiety and depression commonly co-occur during pregnancy and may increase risk of poor birth outcomes including preterm birth and low birth weight. Our understanding of rates, patterns, and predictors of comorbid anxiety and depression is hindered given the dearth of literature, particularly in low- and middle-income (LMI) countries. The aim of this study is (1) to explore the prevalence and patterns of comorbid antenatal anxiety and depressive symptoms in the mild-to-severe and moderate-to-severe categories among women in a LMI country like Pakistan and (2) to understand the risk factors for ...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
D, Eszter B Abstract Preclinical studies suggest that stress-related disorders even prior gestation can cause long-term changes at the level of neurobehavioral adaptations. Therefore, it is critical to consider undergoing antidepressant therapy which could reverse the negative consequences in the offspring. Venlafaxine is widely used in clinical practice; however insufficient amount of well-controlled studies verified the safety of venlafaxine therapy during gestation and lactation. The aim of this work was to investigate the effects of perinatal venlafaxine therapy on selected neurobehavioral variables in mothers...
Source: Behavioural Brain Research - Category: Neurology Authors: Tags: Behav Brain Res Source Type: research
Children of women who used cannabis while they knew they were pregnant may be at greater risk of symptoms of mental illness than children of women who did not use cannabis during pregnancy, according to areport inJAMA Psychiatry. For instance, youth who were exposed to cannabis in the womb were more likely to report more psychotic-like experiences, as well as problems with aggressive behavior, depression, and anxiety than those without such exposure.“[P]regnant women, and even those contemplating pregnancy, should be discouraged from using any cannabis by health care professionals, dispensaries, and others,” wr...
Source: Psychiatr News - Category: Psychiatry Tags: ABCD study agression anxiety cannabis depression JAMA Psychiatry pregnancy psychotic-like experiences Source Type: research
Condition:   Covid19 Interventions:   Other: State-trait anxiety inventory scale;   Other: Edinburgh Postnatal Depression Scale (EDPS) Sponsor:   Assiut University Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionsSupervised group exercise did not improve psychological well ‐being for women with or at high risk of depression at 29‐34 weeks of gestation. Eight weeks postpartum the intervention group reported significantly higher psychological well‐being than the control group. Based on our results, supervised exercise in groups is a safe complementary course of t reatment alongside the existing antenatal care.
Source: Acta Obstetricia et Gynecologica Scandinavica - Category: OBGYN Authors: Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
During the perinatal and postpartum period, women are vulnerable to mental health disorders. Primary care providers are skilled at screening, diagnosing, and treating the mother for postpartum depression. However, perinatal and postpartum anxiety demonstrates a greater prevalence rate and appears to be under-recognized and under-treated, despite its increased prevalence. With frequent patient encounters during pregnancy and in the postpartum period, nurse practitioners have the opportunity to recognize and treat postpartum anxiety and, as a result, improve patient outcomes for the mother and infant.
Source: The Journal for Nurse Practitioners - Category: Nursing Authors: Tags: Featured Article Source Type: research
CONCLUSIONS: In pregnancy, women show less stress and less psychopathological symptoms than in post-natal period. During pregnancy women are more anxious and somatise more than men. After birth, they keep somatising more. Also, in perinatal period, women's changes are more salient. The association of conjugality and motherhood-fatherhood development should be deepened in future investigation. PMID: 32877260 [PubMed - as supplied by publisher]
Source: Journal of Reproductive and Infant Psychology - Category: Psychiatry & Psychology Tags: J Reprod Infant Psychol Source Type: research
Maternal obesity has severe physical impacts such as increased chances of pre-eclampsia and gestational diabetes. However, mental health impacts are given less attention within antenatal care. Evidence suggest...
Source: BMC Pregnancy and Childbirth - Category: OBGYN Authors: Tags: Research article Source Type: research
Prevention of childhood caries is an ongoing public health challenge, but the possibility of an association with maternal mental disorders has received limited attention. We estimated the extent to which maternal mental disorders are associated with an increased risk of hospitalization due to dental caries. We conducted a longitudinal cohort study of 790,758 infants born in Quebec, Canada between 2006 and 2016, with follow-up extending to 2018. We identified women with mental disorders before or during pregnancy and computed the incidence of dental caries in their children. We estimated HR and 95% CI for the association of...
Source: Caries Research - Category: Dentistry Source Type: research
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