Human papillomavirus-positivity is associated with EREG down-regulation and promoter hypermethylation in head and neck squamous cell carcinoma.

CONCLUSION: We conclude that EREG is the target of epigenetic regulation in HPV+ HNCs and its suppressed expression through promoter hypermethylation is associated with the development of HPV-associated HNCs.
PMID: 33007298 [PubMed - as supplied by publisher]

Source: Experimental and Molecular Pathology - September 28, 2020 Category: Pathology Authors: Khanal S, Strickley JD, Ha T, Demehri S, Ghim SJ, Jenson AB, Redman RA, Joh JJ Tags: Exp Mol Pathol Source Type: research